Research groups

Bioanalytical chemistry

Utilizing modern separation methods – high-performance liquid chromatography and capillary electrophoresis for qualitative and quantitative analyses of biologically compounds (enzymes, clinical diagnostics, medicinal plants, and others).

Environmental biotechnology

Study of bacterial oxidation of iron and inorganic sulphur compounds on the cellular and enzymatic level in relation to the activity of acidophilic chemolithotrophic bacteria in biohydrometallurgy and environment.

Molecular pathology

Research of interactions between the host and the pathogen in plants. Searching for molecular patterns in human and plant diseases, changes in DNA and RNA during the development of a disease.

Immunoassays and Nanosensors

Development of immunochemical assays and sensors, use of nanomaterials as immunoassay labels.

Biochemistry of denitrification bacteria

Distribution of electron flow in branched respiratory pathways. Intracellular nitrate transport. Enzymology of flavin-dependent oxidoreductases FerA and FerB. Feedback of bacterial proteome on changes of growth conditions.

Glycobiochemistry

Structural and functional study of proteins involved in specific recognition of biologically active glycoconjugates and specific interaction between the host and pathogen.

Cancer proteomics

Study of molecular processes in the development of solid tumours and metastases using proteomics. Identification of biomarkers, molecular targets and its possible therapeutic modulation using methods of cellular and molecular biology.

Bioanalytical chemistry on the nanometer scale

Developing sensitive bioanalytical techniques with the ultimate goal to detect single molecules of an analyte. Focused on research using photon-upconversion nanoparticles and single-molecule analyses in femtoliter volumes.

Biosensors

Development of electrochemical and piezoelectrical biosensors, application of enzyme electrodes and immunosensors in the environment and clinical field. Study of affinity interactions in real-time using biosensors

Molecular physiology

DNA testing of genetic diseases and DNA diagnostics of viral and bacterial diseases in human and veterinary medicine.

Secondary metabolites

Development of methods for assessing low-molecular-weight biomolecules (LC/MS, TOF, q-TOF, FLD, DAD). Study of phytoalexins and phytoestrogen metabolism.

Biomolecular structure in cellular communication

Integrating NMR spectroscopy with cellular biology to study mitochondrial nucleic acids and proteins and their roles in cellular signaling, metabolism, and immune responses, with biomolecules analyzed in native conditions to uncover principles of cellular adaptation.