Utilizing modern separation methods – high-performance liquid chromatography and capillary electrophoresis for qualitative and quantitative analyses of biologically compounds (enzymes, clinical diagnostics, medicinal plants, and others).

Bioanalytic chemistry

Study of bacterial oxidation of iron and inorganic sulphur compounds on the cellular and enzymatic level in relation to the activity of acidophilic chemolithotrophic bacteria in biohydrometallurgy and environment.

Environmental biotechnology

Research of interactions between the host and the pathogen in plants. Searching for molecular patterns in human and plant diseases, changes in DNA and RNA during the development of a disease.

Molecular pathology

Development of immunochemical assays and sensors, use of nanomaterials as immunoassay labels.

Immunoassays and Nanosensors

Distribution of electron flow in branched respiratory pathways. Intracellular nitrate transport. Enzymology of flavin-dependent oxidoreductases FerA and FerB. Feedback of bacterial proteome on changes of growth conditions.

Biochemistry of denitrification bacteria

Structural and functional study of proteins involved in specific recognition of biologically active glycoconjugates and specific interaction between the host and pathogen.

Glycobiochemistry

Study of molecular processes in the development of solid tumours and metastases using proteomics. Identification of biomarkers, molecular targets and its possible therapeutic modulation using methods of cellular and molecular biology.

Cancer proteomics

Developing sensitive bioanalytical techniques with the ultimate goal to detect single molecules of an analyte. Focused on research using photon-upconversion nanoparticles and single-molecule analyses in femtoliter volumes.

Gorris group

Development of electrochemical and piezoelectrical biosensors, application of enzyme electrodes and immunosensors in the environment and clinical field. Study of affinity interactions in real-time using biosensors

Biosensors

DNA testing of genetic diseases and DNA diagnostics of viral and bacterial diseases in human and veterinary medicine.

Molecular physiology

Development of methods for assessing low-molecular-weight biomolecules (LC/MS, TOF, q-TOF, FLD, DAD). Study of phytoalexins and phytoestrogen metabolism.

Secondary metabolites